Recently, Professors Chu Bo and Han Lihui from the School of Basic Medical Sciences, serving as co-corresponding authors, published a research paper titled “S100P is a ferroptosis suppressor to facilitate hepatocellular carcinoma development by rewiring lipid metabolism” in Nature Communications. The study identified the calcium-binding protein S100P as a key molecule mediating the resistance of hepatocellular carcinoma cells to ferroptosis, clarified the effector mechanism by which S100P enables hepatocellular carcinoma cells to resist ferroptosis, and provided a novel target for hepatocellular carcinoma treatment targeting ferroptosis. Yang Min, a doctoral student from the School of Basic Medical Sciences, Shandong University, and Cui Weiwei, a postdoctoral fellow from Qilu Hospital of Shandong University, are the co-first authors of this paper. Shandong University acts as the first author’s affiliation and the corresponding author’s affiliation.