YanminZhang
M.D. /Associate professor/ Tutor for Ph.D. graduate
School of Basic Medical Sciences, Shandong University
44 Wenhua Xi Road, Jinan, Shandong 250012, P.R.China
ymzhang@sdu.edu.cn
Room:6234, Building6
Phone: (0531)88382047
Education
2000–2003M.D. Histology&Embryology,LuzhouCollege,Luzhou, China
1995– 2000B.S. in Clinical Medicine,Taishan College, Jinan, China
Experience
2016-Present Associate Professor, Tutor for graduate, Department of Human Anatomy and Histology Embryology, School of Basic Medical Sciences, Shandong University
2005– 2015Lecturer, Tutor for graduate,Department of Human Anatomy and Histology Embryology, Shandong University School of Medicine
2008 – 2009 Visiting Scholar, Laboratory of Neurobiology,Department of Neurology,Boston University
Research
Explorethe mechanism of etiology and pathogenesis of glioma and abnormal brain development
Projects
1.GRIM-19 promoted autophagy and the related mechanisms in development of glioma
2.Stathmin/SCLIP involve in development of glioma
Publications
1.Li H# ,Zhang Y# ,Liu S,Li F,Wang B,Wang J，Cao L,Xia T,Yao Q,Chen H,Zhang Y,Zhu X,Li Y,Li G,Wang J,Li X,Ni S.Melatonin Enhances Proliferation and Modulates Differentiation of Neural Stem Cells Via Autophagy in Hyperglycemia.Stem Cells.2019 Apr;37(4):504-515. doi: 10.1002/stem.2968. Epub 2019 Jan 14.
2.Zhang Y,Guo O, Huo Y, Wang G, Man HY.Amyloid-β Induces AMPA Receptor Ubiquitination and Degradation in Primary Neurons and Human Brains of Alzheimer's Disease. J Alzheimers Dis. 2018;62(4):1789-1801.
3.Liu Q, Wang L, Wang Z, Yang Y, Tian J, Liu G, Guan D, Cao X,Zhang Y*, Hao A.GRIM-19 opposes reprogramming of glioblastoma cell metabolism via HIF1α destabilization.Carcinogenesis. 2013 Aug;34(8):1728-36
4.Zhang Y,Liu Q,Wang F,Ling EA,Liu S,Wang L,Yang Y,Yao L,Chen X,Wang F,Shi W,Gao M,Hao A. Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α.J Pineal Res.2013 Sep;55(2):121-30.
5.Zhang Y, Hao H, Zhao S, Liu Q, Yuan Q, Ni S, Wang F, Liu S, Wang L, Hao A.
Downregulation of GRIM-19 promotes growth and migration of human glioma cells.Cancer Sci. 2011 Nov;102(11):1991-9.
6.Zhang Y,Ni S,Huang B,Wang L,Zhang X,Li X,Wang H,Liu S,Hao A,Li X. Overexpression of SCLIP promotes growth and motility in glioblastoma cellsCancer Biol Ther.2015;16(1):97-105.
7.Zhang Y,Du Z1,Zhuang Z2,Wang Y3,Wang F1,Liu S1,Wang H1,Feng H1,Li H1,Wang L1,Zhang X1,Hao A4. E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling.J Neurooncol.2015 Nov;125(2):265-75.
8.Wang H, Feng H,Zhang Y*Resveratrol inhibits hypoxia-induced glioma cell migration and invasion by the p-STAT3/miR-34a axis.
Neoplasma. 2016;63(4):532-9.
9.Zhang Y, He K, Wang F, Li X, Liu D.Notch-1 signaling regulates astrocytic proliferation and activation after hypoxia exposure.Neurosci Lett. 2015 Aug 31;603:12-8.
Teaching andCourse:
Histology&embryology
