Chengjiang Gao

Position: Dean of School of Basic Medical Sciences

Research Interests

Infection & Innate immunity

Education Background

PhD. 1995- 2000, Chinese Academy of Sciences, China

Bachelor. 1991 - 1995, Shandong University, China

Professional Employments

2007-present Professor in Shandong University, China

2002-2007 Research Associate in Duke University, USA

2001-2002 Postdoc in University of California in Davis, USA

Honors& Awards

1. Second prize of State Scientific and Technological Progress Award, 2018

2. Changjiang Scholar, 2017

3. National Distinguished Young Scholar, 2015

4. Mount Taishan Scholar, 2007

Selected Publications

1) Liu B, Zhang M, Chu H, Zhang H, Wu H, Song G, Wang P, Zhao K, Hou J, Wang X, Zhang L,Gao Chengjiang*. 2016. The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination. Nat Immunol. 2017 Feb;18(2):214-224.

2) Song H, Liu B, Huai W, Yu Z, Wang W, Zhao J, Han L, Jiang G, Zhang L,GaoChengjiang*, Zhao W*. 2016. The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3. Nat Commun. 2016 Dec 8; 7:13727.

3) Song G, Liu B, Li Z, Wu H, Wang P, Zhao K, Jiang G, Zhang L,Gao Chengjiang*. 2016. E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1. Nat Immunol. 17(12):1342-1351.

4) Wang P, Zhao W, Zhao K, Zhang L,Gao Chengjiang*. 2015. TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3. Plos Pathog. 11(3), e1004726.

5) Zhang M, Wang L, Zhao X, Zhao K, Meng H, Zhao W*,Gao Chengjiang*. 2012. TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1. J. Exp. Med. 209(10): 1703-1711.

COURSES

Molecular &Cellular Immunology

CONTACTS

Phone: 0531-88382292

Email: cgao@sdu.edu.cn