Bingyu Liu, M.D

RESEARCH FIELD

Infection and Innate Immunity

Personal profile

Dr. Bingyu Liu graduated from Shandong University Medical School in 2017 and received her M.D degree. Dr. Liu is currently Assistant Professor in Department of Medical Immunology, School of Basic Medical Sciences, Shandong University. She is also the Vice President and Secretary General of the Youth Committee of Shandong Immunology Society. Over the years, Dr. Liu has been engaged in systematic research on the mechanism of E3 ubiquitin ligase regulating innate immune signal transduction, and has obtained a series of internationally influential original achievements. As the first author, she has published many papers onNature Immunology、Nature Communication、Current Opinion in Immunologyand other internationally renowned Immunology journals. She has been awarded Shandong excellent doctoral thesis award、Shandong excellent graduate、Young scholar award of Chinese society of immunology and so on. She was selected into China Postdoctoral Innovative Talent Support Program in 2017 andShandong University Cheeloo Young Scholars Future Plan in 2018.

EDUCATION

Institution Dates Degree Subject

Jining medical college, China 2007-2012 Bachelor Medicine

Shandong University, China 2012-2017 M.D Immunology

AWARDS

2017 Shandong Excellent Graduate

2018 Shandong Excellent Doctoral Thesis Award

2018 Excellent Paper Award of Chinese Society of Cell Biology

2018 Young Scholar Award of Chinese Society of Immunology

PUBLICATIONS

1.Liu B^#, Zhang M^#, Chu H, Zhang H, Wu H, Song G, Wang P, Zhao K, Hou J, Wang X, Zhang L, Gao C*. The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination.Nat Immunol. 2017 Feb; 18(2):214-224.F1000 Prime Recommend. Co-First Authour

2.Song H^#,Liu B^#, Huai W^#, Yu Z, Wang W, Zhao J, Han L, Jiang G, Zhang L, Gao C*, Zhao W*. The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3.Nat Commun. 2016 Dec 8; 7:13727. Co-First Authour

3.Liu B^#, Gao C*. Regulation of MAVS activation through post-translational modifications.Curr Opin Immunol. 2017 Dec 12;50:75-81. First Authour

4.Song G^#,Liu B, Li Z, Wu H, Wang P, Zhao K, Jiang G, Zhang L, Gao C*. E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1.Nat Immunol. 2016 Dec; 17(12): 1342-1351.

5.Zhao K^#, Zhang M, Zhang L, Wang P, Song G,Liu B, Wu H, Yin Z, Gao C*. Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response.Sci Rep. 2016 Mar 30;6:23771.

PERSONAL

Office: Room 6518, teaching building No.6

No.44, Wen Hua Xi Road, Jinan, Shandong, P.R. China, 250012

E-mail: liubingyu@sdu.edu.cn

Telephone:+86-531-8382038