Suxia Liu
Prof., M.D., Ph.D., working in the department of immunology, Shandong University School of Basic Medical Sciences. Scientific interest mainly focuses onthe roles of TIPE family on atherosclerosis, hepatitis B and cancer.
Grants
2019-2022 Principal investigator, National Natural Science Foundation of China (No.81873864). Mechanism study of TNFAIP2 in atherosclerosis by regulating macrophages functions.
2012-2015 Principal investigator, National Natural Science Foundation of China (No.81171578). Mechanism study of TIPE2 in Hepatitis B Virus infection by regulating CD8+T cell functions.
2012-2014 Principal investigator, National Natural Science Foundation of China (No.81100205). Mechanism study of TIPE2 in atherosclerosis by negatively regulating macrophages functions.
Publications：
1. Lian K, Ma C, Hao C, Li Y, Zhang N, Chen YH, andLiu S*. TIPE3 protein promotes breast cancer metastasis through activating AKT and NF-kB signaling pathways. Oncotarget, 2017;8(30):48889-48904.
2. Hao C, Zhang N, Geng M, Ren Q, Li Y, Wang Y, Chen YH., andLiu S*. Clinical Significance of TIPE2 Protein Upregulation in Non-Hodgkin’s Lymphoma.J Histochem Cytochem.2016; 64(9):556-564
3. Zhang G, Zhao L, Wang Y, Shao J, Cui J, Lou Y, Geng M, Zhang N, Chen YH, Liu S*. TIPE2 protein prevents injury-induced restenosis in mice. Biochimica et Biophysica Acta. 2015, 1852: 1574-1584
4.Zhang W,Zhang J,Zhao L,Shao J,Cui J,Guo C,Zhu F,Chen YH,Liu S*. TIPE2 protein negatively regulates HBV-specific CD8+ T lymphocyte functions in humans.Mol Immunol.2015; 64(1):204-9.
5. Cui J,Hao C,Zhang W,Shao J,Zhang N,Zhang G,Liu S*. The Identical Expression Profiling of Human and Murine TIPE3 Protein Reveals Links to Its Functions.J Histochem Cytochem.2015; 63(3):206-16.
6.Lou Y,Zhang G,Geng M,Zhang W,Cui J,Liu S*. TIPE2 negatively regulates inflammation by switching arginine metabolism from nitric oxide synthase to arginase.PLoS One.2014;9(5):e96508.
7.Lou Y,Liu S*,Zhang C,Zhang G,Li J,Ni M,An G,Dong M,Liu X,Zhu F,Zhang W,Gao F,Chen YH*,Zhang Y*. Enhanced atherosclerosis in TIPE2-deficient mice is associated with increased macrophage responses to oxidized low-density lipoprotein.J Immunol.2013;191(9):4849-57.
8. Zhang G, Zhang W, Lou Y, Xi W, Cui J, Geng M, Zhu F, Chen YH, Liu S*.TIPE2 deficiency accelerates neointima formation by downregulating smooth muscle cell differentiation.Cell Cycle 2013;12(3):501-10.
