Lei Zhang

Experimentalist., M.D., Ph.D., working in the department of immunology, Shandong University School of Basic Medical Sciences. Scientific interest mainly focuses on the regulation molecular mechanisms of innate immunity, especial anti-fungal immunity.

Grants:

1.Regulation mechanism of IKIP expression and its roles in Toll-like Receptor-triggered immune responses. Principal investigator, National Natural Science Foundation of China, 2016/01-2019/12, (No.81873864).

2.The roles and mechanisms of TRIM31 in antiviral responses. Principal investigator, China Postdoctoral Science Foundation, 2017/01-2018/12 (No.2016M602147).

Publications：

1.Zhang L, Zhao X, Zhang M, Zhao W, Gao C*，Ubiquitin-specific protease 2b negatively regulates IFN-β production and antiviral activity by targeting TANK-binding kinase 1，J Immunol, 2014, 193(5): 2230-2237.

2.Wang L^#, Zhang L^#, Zhao X, Zhang M, Zhao W*, Gao C*, Lithium attenuates IFN-βproduction and antiviral response via inhibition of TANK-binding kinase 1 kinase activity, J Immunol, 2013, 191(8): 4392-4398.