Faliang Zhu M.D.

Room No. 6538,

Sixth building of Baotuquan Campus, SDU

TEL: 0531-88382038

Vicedirectorforteaching of the Department of Immunology, School of Basic Medical Sciences, Shandong University, and Vice Secretary General of the ShandongSociety for Immunology. I graduated from Shandong Normal University with a major in biological education in 1997, graduated from the Shandong Academy of Medical Sciences with a master's degree in immunology in 2000 and obtained doctorate in immunology of Shandong university in 2011. During from 2015 to 2016, I was a visiting scholar at Temple University School of Medicine. Hosted a Shandong Science and Technology Development Plan, a free innovation fund from Shandong University. Participated in a number of National Natural Science Fund and provincial and ministerial research projects, participated in a national 973 project research, in recent years, mainly engaged in the study of the immune mechanism of the occurrence and development of atherosclerosis.

Paper:

1.Zhu F, Wang Q, Guo C, Wang X, Cao X, Shi Y, Gao F, Ma C, Zhang L*. IL-17 induces apoptosis of vascular endothelial cells - A potential mechanism for human acute coronary syndrome.Clin Immunol. 2011 Nov;141(2):152-60

2.Li N#,Zhu F#, Gao F, Wang Q, Wang X, Li H, Ma C, Sun W, Xu W, Wang C, Zhang L*. Blockade of CD28 by a synthetical peptoid inhibits T-cell proliferation and attenuates graft-versus-host disease. Cell Mol Immunol. 2010 Mar;7(2):133-42

3.Feng D, Dai S, Liu F, Ohtake Y, Zhou Z, Wang H, Zhang Y, Kearns A, Peng X,Zhu F, Hayat U, Li M, He Y, Xu M, Zhao C, Cheng M, Zhang L, Wang H, Yang X, Ju C, Bryda EC, Gordon J, Khalili K, Hu W, Li S, Qin X*, Gao B*. Cre-inducible human CD59 mediates rapid cell ablation after intermedilysin administration. J Clin Invest. 2016 Jun 1;126(6):2321-33.

4.Song X,Zhang X,Wang X,Zhu F,Guo C,Wang Q,Shi Y, Wang J, Chen Y, Zhang L*.Tumor suppressor gene PDCD4 negatively regulates autophagy by inhibiting the expression of autophagy-related gene ATG5. Autophagy.2013 May;9(5):743-55.

5.Ma T, Gao Q,Zhu F, Guo C, Wang Q, Gao F, Zhang L*.Th17 cells and IL-17 are involved in the disruption of vulnerable plaques triggered by short-term combination stimulation in apolipoprotein E-knockout mice. Cell Mol Immunol.2013 Jul;10(4):338-48.

6.Li H,Zhang X,Song X,Zhu F,Wang Q,Guo C,Liu C,Shi Y,Ma C,Wang X,Zhang L.PDCD5 promotes cisplatin-induced apoptosis of glioma cells via activating mitochondrial apoptotic pathway.Cancer Biol Ther.2012 Jul;13(9):822-30.

7.Qi Gao, Yang Jiang, Tian Ma,Faliang Zhu,Fei Gao, Zhang, Chun Guo, Qun Wang, Xiaoyan Wang, Chunhong Ma, Yun Zhang, Wanjun Chen and Lining Zhang*. A Critical Function of Th17 Proinflammatory Cells in the Development of Atherosclerotic Plaque in Mice.J Immunol2010;185;5820-5827.

8.Wang Q, Liu C,Zhu F, Liu F, Zhang P, Guo C, Wang X, Li H, Ma C, Sun W, Zhang Y, Chen W, Zhang L*.Reoxygenation of hypoxia-differentiated dentritic cells induces Th1 and Th17 cell differentiation. Mol Immunol. 2010 Jan;47(4):922-31.

Academic Award

Role and mechanism of new T cell subsets Th17 and Treg in inflammation-related diseases. shandong provincial people's government. Third prize of shandong science and technology award (natural science), 2015. (No. 3)

The role and regulation mechanism of PDCD4 in inflammation and tumor, shandong provincial department of education, outstanding scientific research achievement award, first prize, 2014. (No.4)

The role of T cell immunity in immune-related diseases and its regulatory mechanism, shandong provincial department of education, outstanding scientific research achievement award (natural science), third prize, 2011. (No. 3)

Teaching Material：

“Medical immunology and pathogen biology experiment”Chief editor zhou yabin，Science Press; Second Edition.