Faculty
Department of Pathogenic Biology
Wei Tang



Wei Tang

My Research

The role of growth factors and cytokines in the pathogenesis of acute kidney injury and chronic kidney disease. The repair and clearance of DNA and RNA damage in renal cells responding to pathological conditions.

Positions

2003-2005: Teaching Assistant, School of Basic Medical Sciences, Shandong University

2005-2011: Lecturer, School of Basic Medical Sciences, Shandong University

2011-present: Associate Professor, School of Basic Medical Sciences, Shandong University

Education

1996-2000: Bachelor of biotechnology, School of Life Sciences, Shandong University

2000-2003: Master of Microbiology, School of Life Sciences, Shandong University

2007-2011: Doctor of Pathogenic Biology, School of Medicine, Shandong University

Publications

[1] Zhou D*, Zhou M*, Wang Z, Fu Y, Jia M, Wang X, Liu M, Zhang Y, Sun Y, Zhou Y, Lu Y, Tang W#, Yi F#. Progranulin alleviates podocyte injury via regulating CAMKK/AMPK-mediated autophagy under diabetic conditions. J Mol Med (Berl). 2019 Aug 11. doi: 10.1007/s00109-019-01828-3. [Epub ahead of print] (5-Year Impact Factor: 5.114)
[2] Zhou D*, Zhou M, Wang Z, Fu Y, Jia M, Wang X, Liu M, Zhang Y, Sun Y, Lu Y, Tang W#, Yi F#. PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy. Cell Death Dis. 2019 Jul 8;10(7):524. (5-Year Impact Factor: 6.211)
[3] Baojin Ma*, Feng Liu, Shan Zhang, Jiazhi Duan, Ying Kong, Zhao Li, Dongqi Tang, Wenjuan Wang, Shaohua Ge#, Wei Tang#, Hong Liu#. Two-photon fluorescent polydopamine nanodots for CAR-T cell function verification and tumor cell/tissue detection. J. Mater. Chem. B, 2018, 6, 6459-6467. (5-Year Impact Factor: 4.959)
[4] Li X*, Zuo Z, Chen Q, Li J, Tang W#, Yang P#. Progranulin is highly expressed in patients with chronic periodontitis and protects against experimental periodontitis in rats. J Periodontol. 2018 Dec;89(12):1418-1427. (5-Year Impact Factor: 3.522)

[5]Ma B*, Zhang S, Liu F, Duan J, Wang S, Han J, Sang Y, Yu X, Li D,Tang W#, Ge S#, Liu H#.One-Dimensional Hydroxyapatite Nanostructures with Tunable Length for Efficient Stem Cell Differentiation Regulation. ACS Appl Mater Interfaces.2017 Oct 4;9(39):33717-33727. (5-Year Impact Factor: 7.823)

[6]Feng T*, Zheng L*, Liu F, Xu X, Mao S, Wang X, Liu J, Lu Y, Zhao W, Yu X,Tang W#.Growth factor progranulin promotes tumorigenesis of cervical cancer via PI3K/Akt/mTOR signaling pathway.Oncotarget. 2016 Sep 6;7(36):58381-58395. (5-Year Impact Factor: 5.415)

[7]Yu Y*, Xu X, Liu L, Mao S, Feng T, Lu Y, Cheng Y, Wang H, Zhao W,Tang W#. Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock.J Cell Mol Med. 2016 Mar;20(3):506-17. (5-Year Impact Factor: 4.599)

[8]Xu X*, Gou L, Zhou M, Yang F, Zhao Y, Feng T, Shi P, Ghavamian A, Zhao W, Yu Y, Lu Y, Yi F, Liu G#,Tang W#. Progranulin protects against endotoxin-induced acute kidney injury by downregulating renal cell death and inflammatory responses in mice.Int Immunopharmacol. 2016 Sep;38:409- 419. (5-Year Impact Factor: 2.752)

[9]Zhou M*,Tang W*, Fu Y, Xu X, Wang Z, Lu Y, Liu F, Yang X, Wei X, Zhang Y, Liu J, Geng X, Zhang C, Wan Q, Li N, Yi F#.Progranulin protects against renal ischemia/reperfusion injury in mice. Kidney Int.2015 May;87(5):918-29. (5-Year Impact Factor: 7.891)

[10]Lu Y*, Zheng L, Zhang W, Feng T, Liu J, Wang X, Yu Y, Qi M, Zhao W, Yu X#,Tang W#.Growth factor progranulin contributes to cervical cancer cell proliferation and transformation in vivo and in vitro.Gynecol Oncol. 2014 Aug;134(2):364-71. (5-Year Impact Factor: 3.915)

[11]Zheng L*,Tang W*, Wei F, Wang H, Liu J, Lu Y, Cheng Y, Bai X, Yu X#, Zhao W#.Radiation-inducible protein RbAp48 contributes to radiosensitivity of cervical cancer cells. Gynecol Oncol.2013 Sep;130(3):601-8. (5-Year Impact Factor: 3.923)

[12]Tang W*, Lu Y*, Tian QY*, Zhang Y, Guo FJ, Liu GY, Syed NM, Lai Y, Lin EA, Kong L, Su J, Yin F, Ding AH, Zanin-Zhorov A, Dustin ML, Tao J, Craft J, Yin Z, Feng JQ, Abramson SB, Yu XP, Liu CJ#. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science. 2011 Apr 22;332(6028):478-84. (5-Year Impact Factor: 32.452)

My Teaching

Medical Microbiology

Contact Information

Room No. 6508, 6# Building

Tel : +86 0531-88382579

E.mail: weitang@sdu.edu.cn



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