Faculty
Department of Pathogenic Biology
Shili Liu



Shili Liu


Research interest:microbiota; mechanism of gastric cancer

Personal introduction:Associate professor. Before coming to Shandong University, I did postdoctoral research at the University of Washington (Seattle).

Education

2003/9 - 2007/1,Tsinghua University, Ph.D;

2000/9 - 2003/6,Shandong University, Master's degree;

1992/9 - 1996/6,Shandong University, Bachelor's degree.

Publications:

1.Liu Fengyan, Fan Ziyan, Song Ning, Han Mingyong, Yan Ming (*), Guo Liang-Hong, Jia Jihui,Liu Shili(*), XRCC4, which is inhibited by PFDA, regulates DNA damage repair and cell chemosensitivity,J Cell Biochem, , 2019, 120(8): 12665-12676Corresponding author. https://onlinelibrary. wiley.com /doi/abs/10.1002/jcb.28534.

2.Zhang Zhun, Fan Bingbing, Liu Fengyan, Song Ning, Peng Yanping, Ma Wenzheng, Ma Rongtao, Dong Tianyi,Liu Shili(*), HOX transcript antisense RNA is elevated in gastric carcinogenesis and regulated by the NF-κB pathway,J Cell Biochem, 2019, 120(6): 10548-10555(Corresponding author).

3.Zhang Zhun, Song Ning, Peng Yanping, Fan Ziyan, Han Mingyong, Zhao Min, Dong Tianyi,Liu Shili(*),Evironmental pollutant perfluorodecanoic acid upregulates cIAP2 to suppress gastric cell senescence,Oncology Reports,2019, 41(2): 981-988.Corresponding author.

4.ZhangZhun,DongTianyi,FuYing,ZhouWenhong,TianXingsong(*), ChenGengyu,Liu Shili(*), MMP‐11 promotes papillary thyroid cell proliferation and invasion via the NF‐κB pathway,J Cell Biochem, 2019, 120(2): 1860-1868.Corresponding author.

5.Fan Ziyan, Li Zhonghao, Liu Shanshan, Yang Fei, Bian Zhaoyang, Wang Ying, Tang Gangling, Zhao Qinxiao, Deng Huimin (*),Liu Shili(*), Rapid fluorescence immunoassay of benzo[a] pyrene in mainstream cigarette smoke based on a dual-functional antibody–DNA conjugate,RSC Adv., 2018, 8: 29562.Corresponding author.

6.Dong Tianyi, Zhang Zhun, Zhou Wenhong, Zhou Xiangyu, Geng Chong, Chang Lap Kam, Tian xingsong(*),Liu Shili(*), WNT10A/β‑catenin pathway in tumorigenesis of papillary thyroid carcinoma,Oncology Reports,2017,38:1287-1294Corresponding author.

7. Dong Tianyi, Peng Yanping, Zhong Ning, Liu Fengyan, Zhang Hanyu, Xu Mengchen, Liu Rutao, Han Mingyong, Tian Xingsong, Jia Jihui, Chang Lap Kam, Guo Liang-Hong(*),Liu Shili(*), Perfluorodecanoic acid (PFDA) promotes gastric cell proliferation via sPLA2-IIA,Oncotarget, 2017, 8: 50911-50920Corresponding author.

8.Zhou Xiangyu, Dong Tianyi, Fan Ziyan, Peng Yanping, Zhou Rongbin, Wang Xiaqiong, Song Ning, Han Mingyong, Fan Bingbing, Jia Jihui,Shili Liu(*), Perfluorodecanoic acid stimulates NLRP3 inflammasome assembly in gastric cells,Scitific Reports.2017, 7: 45468.Corresponding author.

9. Tianyi Dong, Qiang Feng, Fengyan Liu, Lap Kam Chang, Xiangyu Zhou, Mingyong Han, Xingsong Tian, Ning Zhong(*),Shili Liu(*), Alteration of stomach microbiota compositions in the progression of gastritis induces nitric oxide in gastric cell,Experimental and therapeutic medicine, 2017, 13: 2793-2800Corresponding author.

10. Peng Yanping,Zhao Qian,Zhang Hanyu,Han Bo,Liu Suxia,Han Mingyong,Liu Shili(*),TIPE2, a negative regulator of TLR signaling, regulates p27 through IRF4-induced signaling,Oncology Reports,2016,35:2480-2486Corresponding author.

11.Zhao Qian (#),Zhao Min(#),Dong Tianyi(#),Zhou Chengjun,Peng Yanping,Zhou Xiangyu,Fan Bingbing,Ma Wenzheng,Han Mingyong,Liu Shili(*),Tumor necrosis factor-α-induced protein-8 like-2 (TIPE2) upregulates p27 to decrease gastic cancer cell proliferation,Journal of Cellular Biochemistry,2015, 116: 1121–1129Corresponding author.

12.Liu Shili,Jiang Man,Zhao Qiang,Li Shancheng,Peng Yanping,Zhang Pengfei,Han Mingyong(*),Vascular endothelial growth factor plays a critical role in the formation of the pre-metastatic niche via prostaglandin E2,Oncology Reports,2014,32:2477-2484First author.

13. Yu, Han,Zeng, Jiping,Liang, Xiuming,Wang, Wenfu,Zhou, Yabin,Sun, Yundong,Liu, Shili,Li, Wenjuan,Chen, Chunyan,Jia, Jihui(*),Helicobacter pylori Promotes Epithelial-Mesenchymal Transition in Gastric Cancer by Downregulating Programmed Cell Death Protein 4 (PDCD4),Plos One,2014,9(8):e105306.

14. Wei, Fang,Wang, Xianghua,Peng, Shasha,Jia, Qiuhui,Jiang, Chao,Liu, Shili,Xu, Zhenghu(*),Direct Gold-Catalyzed Regioselective Tetrafunctionalization of Nonactivated Alkynes,Synthesis,2014,46(16): 2168-2174.

15. Tan, Xiaojuan,Liu, Lin,Liu, Shili,Yang, Dongting,Liu, Yikun,Yang, Shuang,Jia, Aiqun(*),Qin, Nan,Genome of Staphylococcus xylosus and Comparison with S. aureus and S. epidermidis,Journal of Genetics and Genomics,2014,41(7):413-416.

16.Liu Shi-Li,Chen Shou-Zhen,Zhao Qian,Xu Zheng-Hu,Li Yu,Jia Ji-Hui,Guo Liang-Hong(*),Photoelectroch emical Competitive Detection of Biotin,Chinese Journal of Analytical Chemistry,2013,41(10):1477-1481First author.

17. Liang, Xiuming,Zeng, Jiping,Wang, Lixiang,Fang, Ming,Wang, Qing,Zhao, Min,Xu, Xia,Liu, Zhifang,Li, Wenjuan,Liu, Shili,Yu, Han,Jia, Jihui,Chen, Chunyan(*),Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212,PLos One,2013,8(7): e69784.

18. Feng, Yimin,Wang, Lixiang,Zeng, Jiping,Shen, Li,Liang, Xiuming,Yu, Han,Liu, Shili,Liu, Zhifang,Sun, Yundong,Li, Wenjuan,Chen, Chunyan,Jia, Jihui(*),FoxM1 is Overexpressed in Helicobacter pylori-Induced Gastric Carcinogenesis and Is Negatively Regulated by miR-370,Molecular Cancer Research,2013,11(8):834-844.

19. Sun, Yundong,Li, Xinpeng,Li, Wen,Zhao, Min,Wang, Lixiang,Liu, Shili,Zeng, Jiping,Liu, Zhifang(*),Jia, Jihui,Proteomic analysis of the function of spot in Helicobacter pylori anti-oxidative stress in vitro and colonization in vivo,Journal of Cellular Biochemistry,2012,113(11):3393-3402.

20. Wang, Hongyan,Sun, Yundong,Liu, Shili,Yu, Han,Li, Wenjuan,Zeng, Jiping,Chen, Chunyan,Jia, Jihui(*),Upregulation of progranulin by Helicobacter pylori in human gastric epithelial cells via p38MAPK and MEK1/2 signaling pathway: role in epithelial cell proliferation and migration,FEMS Immunology and Medical Microbiology,2011,63(1):82-92.

21.LiuShili, TranKenny K., PanSteven, ShenHong(*), Detecting and differentiating microbes by dendritic cells for the development of cell-based biosensors,Biosens Bioelectron, 2009, 24(8):2598-603(First author).

22.Liu Shili, Li Chao, Cheng Jing, Zhou Yuxiang(*),Selective photoelectrochemical detection of DNA with high-affinity metallointercalator and tin oxide nanoparticle electrode,.Anal Chem.,2006, 78(13):4722-6First author.

23. Liang Minmin,Liu Shili, Wei Mingyuan, Guo Liang-Hong(*),Photoelectrochemical oxidation of DNA by ruthenium tris(bipyridine) on a tin oxide nanoparticle electrode,Anal Chem., 2006, 78(2):621-3.

24. Li Chao,Liu Shili, Guo Liang-Hong(*), Chen Depu, A new chemically amplified electrochemical system for DNA detection in solution,Electrochem. Commun., 2005, 7(1): 23-28.

Teaching coursesMedical microbiology; Advances in medical microbiology; Human microbiota.

Office:Room 6504, 6theducation building (Monday to Friday 9:00-17:00).

Contact information:0531-88382579, liushili@sdu.edu.cn.



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