Faculty
Department of Pathology
Cuijuan Zhang

1.Interest in research

Genetics and Epigenetics of Lymphoma

2.Personal Profile

Cuijuan, Zhang, Ph D

Professor

Department of Pathology

Shandong University

2005 Lecturer, Department of Pathology, Shandong University.

2008 Associate professor, Department of Pathology, Shandong University.

2017 Professor, Department ofPathology, Shandong University.

The research focuses on the genetics and epigenetics of lymphoma, and the previous research had been funded by the National Natural Science Foundation of China.

Educational background

2015.1-2016.1 Visiting scholar; Department of Pathology and Micobiology, University of Nebraska Medical Center

2003.4-2003.7 Department of Pathology and Micobiology, The Chinese University of Hong Kong

2000-2005 Ph D Department of Pathology Shandong University

1995-2000 Bachelor of clinical medicine Shandong Medical University

4. Award, Honor

“Outstanding Young Scholar Award” Wu Bing-Quan Foundation for the advancement of pathology. 2012

Provincial Science Prize three (The genetics and epigenetics study for diagnosis and prognosis of liver tumors) 2015

5.Publications

1.Zhang C*, Li H, Wang Y, Liu W, Zhang Q, Zhang T, Zhang X, Han B, Zhou G*. Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications. J Hepatol, 2010; 53(5): 889-95.

2.Zhang C#, Li H#, Zhou G*, Zhang Q, Zhang T, Li J, Zhang J, Hou J, Liew CT, Yin D. Transcriptional silencing of the TMS1/ASC tumor suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. J Pathol, 2007, 212(2): 134-142.

3. Zhang, Xiaoying, Li, Hiu Ming, Liu, Zhiyan, Zhou, Gengyin, Zhang, Qinghui, Zhang, Tingguo, Zhang, Jianping,Zhang, Cuijuan*. Loss of heterozygosity and methylation of multiple tumor suppressor genes on chromosome 3 in hepatocellular carcinoma. J Gastroenterol, 2013, 48(1):132-143.

4. Yao, Shuzhe,Zhang, Jianping , Chen, Haiyan, Sheng, Yan, Zhang, Xiaoying, Liu, Zhiyan,Zhang, Cuijuan*. Diagnostic value of immunohistochemical staining of GP73, GPC3, DCP, CD34, CD31, and reticulin staining in hepatocellular carcinoma. J Histochem Cytochem. 2013, 61(9): 639-648.

5.Cheng Zhang, Yunfgei Peng, Fan Yang, Ruixi Qin, Wenjun Liu,Cuijuan Zhang*. PCDH8 is Frequently Inactivated by Promoter Hypermethylation in Liver

Cancer: Diagnostic and Clinical Significance. Journal of Cancer. 2016, 7(4): 446-452.

6.Sheng, Yan , Wang, Hongtao, Liu, Dongchen, Zhang, Cheng, Deng, Yupeng, Yang, Fan, Zhang, Tingguo*,Zhang, Cuijuan*. Methylation of tumor suppressor gene CDH13 and SHP1 promoters and their epigenetic regulation by the UHRF1/PRMT5 complex in endometrial carcinoma. Gynecologic Oncology, 2016, 140(1): 145-151.

7.Chen, Haiyan, Zhang, Tingguo, Sheng, Yan, Zhang, Cheng, Peng, Yunfei, Wang, Xiao,Zhang, Cuijuan*. Methylation Profiling of Multiple Tumor Suppressor Genes in Hepatocellular Carcinoma and the Epigenetic Mechanism of 3OST2 Regulation. Journal of Cancer. 2015, 6(8): 740-749.

8. Chen, Haiyan#,Zhang, Cuijuan#, Sheng, Yan, Yao, Shuzhe, Liu, Zhiyan, Zhang, Cheng, Zhang, Tingguo*. Frequent SOCS3 and 3OST2 promoter methylation and their epigenetic regulation in endometrial carcinoma. American Journal of Cancer Research. 2015, 5(1): 180-190.

9.Liang K#, Wang J#, Wang Y, Zhou Z, Ge S, Mei S, Li H, Jing X,Zhang C*. The histologic, immunohistochemical, and genetic features of classical Hodgkin lymphoma and anaplastic large cell lymphoma with aberrant T-cell/B-cell antigen expression. Hum Pathol. 2019, 84: 309-320.

10.Zhang C, Ge S, Wang J, Jing X, Li H, Mei S, Zhang J, Liang K, Xu H, Zhang X,Zhang C*. Epigenomic profiling of DNA methylation for hepatocellular carcinoma diagnosis and prognosis prediction. J Gastroenterol Hepatol. 2019 Apr 30. doi: 10.1111/jgh.14694.

6.Teaching Courses

Pathology

7.Contact information

Cuijuan Zhang

Department of Pathology

Shandong University

Wenhuaxi Road 44#

Jinan 250012

China

E-mail: cuijuanzhang@sdu.edu.cn



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