Junhui Zhen, M.D., Ph.D.Dr. Zhen is currently a chief physician in Department of Pathology, Shandong University. She is multi-disciplinary trained in research fields including histopathology and renal biology. Her research interests focus on understanding the molecular mechanisms of glomerulonephritis, viral infectious diseases and tumors. Dr. Zhen specializes in the pathological diagnosis of renal biopsy. She has been engaged in this examination for more than 20 years, with a total number of more than 30000 cases.
BIOGRAPHICAL SKETCH |
NAME Junhui Zhen |
POSITION TITLE Chief physician |
eRA COMMONS USER NAME |
EDUCATION/TRAINING(Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) |
INSTITUTION AND LOCATION |
DEGREE (if applicable) |
YEAR(s) |
FIELD OF STUDY |
Southwest Medical Center of the University of Texas Shandong University, School of Medicine, China |
Post-doctoral Ph.D. |
2008 2008 |
Renal Pathology Pathology |
Shandong University, School of Medicine, China |
M.S. |
2004 |
Pathology |
Shandong University, School of Medicine, China |
M.D. |
1998 |
Medicine |
Employment
1998 – 2002 Assistant Lecturer, Department of Pathology,Shandong University, School of Medicine, China
2003 – 2007 Lecturer, Department of Pathology,Shandong University, School of Medicine, China
2008 – 2017 Deputychief physician/Associate professor, Department of Pathology,Shandong University, School of Medicine, China
2018 – Chief physician, Department of Pathology,Shandong University, School of Medicine, China
Research Fundings
1.“Study on the application value and mechanism of malignant progression of IFI16 in cervical epithelial lesions associated with HPV infection”. National Natural Science Foundation of China(81972436, 2019).
2. “The molecular mechanism of aim2 in the pathogenesis of HBV associated glomerulonephritis”. National Natural Science Foundation of China (81440729，2014).
3. “Study on the application of biosensor in the separation and detection of tumor cells in peripheral blood”. Independent Innovation Fund of Shandong University (2014JC033，2014).
4 . “Perception of HBV DNA in renal proper cells by PHYIN family proteins involved in the pathogenesis of HBV associated glomerulonephritis”. Natural Science Foundation of Shandong Province (2014GSF118122, 2014)
5. “The role of AIM2 and Caspase-1 in the pathogenesis of HBV associated glomerulonephritis”. Natural Science Foundation of Shandong Province (2010TS101, 2010)
Selected Peer-Reviewed Publications
1.Tang, Lijun; Yao, Jing; Kong, Xianglei; Sun, Qing; Wang, Zunsong; Zhang, Ying; Wang, Ping; Liu, Yipeng; Li, Wenbin; Cui, Meiyu;Zhen, Junhui *.Xu, Dongmei , Increasing prevalence of membranous nephropathy in patients with primary glomerular diseases: A cross-sectional study in China , NEPHROLOG Y, 2017.2, 22(2): 168~173
2.Zhang, Hao ; Liu, Yu; Gao, Jian ;Zhen, Junhui*, A sensitive SERS detection of miRNA using a label-free multifunctional probe. , Chem Commun (Camb), 2015.12.7, 51(94): 16836~16839
3.Ye, Ting ;Zhen, Junhui*; Du, Yong ; Zhou, Jason K.; Peng, Ai; Vaziri, Nosratola D.; Mohan, Chandra; Xu, Yan ; Zhou, Xin J. , Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate Restores Nrf2 Activity and Ameliorates Crescentic Glomerulonephritis , PLOS ONE, 2015.3.18, 10(3)
4.Song Ning-Ning; Zhang Hao; Li Jin-Bo;Zhen Jun-Hui*; Gao Jian , Electrokinetic Separation of Polystyrene Microspheres in Conductive Media on a Microfluidic Chip , CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2015.2, 43(2): 176~180
5.Zhen, Junhui*; Zhang, Le ; Pan, Jiachao; Ma, Shumin; Yu, Xiaojian;(*) Li, Xiaobo; Chen, Shijun ; Du, Wenjun , AIM2 Mediates Inflammation-Associated Renal Damage in Hepatitis B Virus-Associated Glomerulonephritis by Regulating Caspase-1, IL-1 beta, and IL-18 , MEDIATORS OF INFLAMMATION, 2014.2.20, 10(1155)
6.Zhen, Junhui*; Li, Qian; Zhu, Yanji; Yao, Xiujun; Wang, Li; Zhou, Aihua; (*) Sun, Shuzhen , Increased serum CXCL16 is highly correlated with blood lipids, urine protein and immune reaction in children with active nephrotic syndrome , DIAGNOSTIC PATHOLOGY, 2014.1.24, 9
7.Du, Wenjun ;Zhen, Junhui*; Zheng, Zhaomin; Ma, Shumin; Chen, Shijun, Expression of AIM2 is high and correlated with inflammation in hepatitis B virus associated glomerulonephritis , JOURNAL OF INFLAMMATION-LONDON, 2013.12. 10, 10
8.Du, Wen-Jun ; Zhen, Jun-Hui*; Zeng, Zhao-Qing; Zheng, Zhao-Min; Xu,(*)Yan; Qin, Lai-Ying; Chen, Shi-Jun , Expression of Interleukin-17 associated with disease progression and liver fibrosis with hepatitis B virus infection: IL-17 in HBV infection , DIAGNOSTIC PATHOLOGY, 2013.2.28, 8
9.Lu, Hua ;Zhen, Junhui*; Wu, Tianfu ; Peng, Ai; Ye, Ting; Wang, Tao; Yu, Xueqing; Vaziri, Nosratola D.; Mohan, Chandra ; Zhou, Xin J. , Supe roxide dismutase mimetic drug tempol aggravates anti-GBM antibody-induced glomerulonephritis in mice , American Journal of Physiology - Renal Fluid and Electrolyte Physiology, 2010.8, 299(2): F445~F452
Teaching Courses
1. Pathology
2.Molecular pathology technology
Contact Information
1. Address: Room 6209, Research Building No. 6
2. Phone Number: (0531) 88382574
3. E-mail: zhendianjing@126.com
