Basic Information:
Name:Bo Chu
Birth: 01-01-1987
Address:School of Basic Medical Science, Shandong University, Jinan, Shandong, 250012
Phone:15688609792 E-mail:chubo123@sdu.edu.cn
Educational experience:
2015.9– 2019.9: Postdoctoral Research Fellow of Cancer Genetics
Department of Pathology and Cell Biology, Columbia University , USA
2009.9 – 2015.3: Ph.D student of Molecular Cell Biology
Dept. of Life Sciences, University of Science & Technology of China
Supervisor: Prof. Mian Wu
Graduation Date:2015.3
2005.9 - 2009.7: B.S. Degree in Cell Biology
Dept. of Life Sciences, University of Science & Technology of China
Supervisor: Prof. Jing Liu
Work experience:
2019.10-present: Professor, School of Basic Medical Science, Shandong University
2015.9– 2019.9: Postdoctoral Research Fellow of Cancer Genetics
Department of Pathology and Cell Biology, Columbia University, USA
Research Focus:
This research group uses the interdisciplinary fields of developmental biology, molecular biology, biochemistry, genetics, cell biology and bioinformatics to study how ferroptosis affects the development of tumors, and how ferroptosis achieves the escape of tumor cells by inhibiting the function of immune cells in tumor microenvironment.
Awards:
2014.6: PhD thesis innovation support plan in USTC
2005.9: Second Prize for excellent new students in USTC
Publications:
·Chu Bo, Ning Kon, Delin Chen, Tong Liu, Le Jiang, Shujuan Song,
Tongyuan Li, Omid Tavana, and Wei Gu*. Specific Requirement for ALOX12 in p53-mediated Tumor Suppression Reveals A Distinct Pathway of Ferroptosis. Nature cell biology2019May 21(5):579-591. doi: 10.1038/s41556-019-0305-6. Epub 2019 Apr 8. IF=19.064
·Delin Chen, Omid Tavana,Bo Chu, Luke Erber, Yue Chen, Richard Baer, and Wei Gu. NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression.Molecular Cell68, 224–232 October 5, 2017. IF=14.248
·Yang Ou, Shang-Jui Wang, Dawei Li, Bo Chu, and Wei Gu. Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses. PNAS November 1, 2016 113 (44) E6806-E6812. IF=9.7
·Chu Bo,Liangwen Zhong, Shuang Dou, Jun Wang, Jianmin Li, Mingwei Wang, Qinghua Shi, Yide Mei, and Mian Wu.miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor[J].Journal of molecular cell biology, 2015, 7(1): 12-22. IF=6.459
·Chu Bo, Ting Wu, Lin Miao, Yide Mei and Mian Wu.MiR-181a regulates lipid metabolism via IDH1.Scientific Reports.2015 March 05; doi:10.1038/srep08801. IF=5.228
