Dexiang Liu

Associate Professor

Department of Medical Psychology and Ethics, School of Basic Medical Sciences, Shandong University, 44#, Wenhua Xi Road, Jinan, Shandong, 250012, P.R. China.

Telephone: 86-531-88382039

E-mail: liudexiang@sdu.edu.cn

Location: Teaching Building 5, Room 303

Education

2019.01-2019.04 Visiting scholar, Language and Culture Institute, University of Virginia Tech, USA

2016.01-2017.01 Visiting scholar, Department of Pharmacology and Nutritional Sciences, University of Kentucky, USA

2008.01-2009.01 Visiting scholar, Department of physiology, University of Kentucky, USA

2006-2011 PH.D., Physiology, Shandong University School of Medicine

2000-2003 M.S., Physiology, Shandong University School of Medicine

Courses

Medical Psychology

Behavior Science

Research interests

Etiology and pathogenesis of mental disorders such as major depressive disorder and PTSD

Publications

（1）Dexiang Liu^#, Zunji Ke , Jia Luo*. Thiamine Deficiency and Neurodegeneration: the Interplay Among Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy. Mol Neurobiol. 2017, 4(7):5440-5448.

（2）Dexiang Liu^#, Qingrui Zhang, Jianhua Gu , Xueer Wang , Kai Xie , Xiuying Xian , Jianmei Wang, Hong Jiang , Zhen Wang*. Resveratrol prevents impaired cognition induced by chronic unpredictable mild stress in rats. Progress in neuro-psychopharmacology & biological psychiatry, 2014, 3(49):21-9

（3）Dexiang Liu^#, Zhen Wang, Ze Gao, Kai Xie, Qingrui Zhang, Hong Jiang, Qi Pang*. Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress. Behavioural brain research,2014,271:116-21

（4）Dexiang Liu^#, Kai Xie, Xudong Yang, Jianhua Gu, Li Ge, Xueer Wang, Zhen Wang*.Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats. Behavioural brain research, 2014, 264:9-16

（5）Dexiang Liu^#, ZhenWang, Jingmin Zhan, Qun Zhang, Jianmei Wang, Qingrui Zhang, Xiuying Xian, Qinsong Luan, Aijun Hao*.Hydrogen sulfide promotes proliferation and neuronal differentiation of neural stem cells and protects hypoxia-induced decrease in hippocampal neurogenesis.Pharmacol Biochem Behav, 2014, 116: 55-63

（6）Zhen Wang^#,Dexiang Liu^#, Fuwu Wang, Shangming Liu, Shidou Zhao, Eng-Ang Lingand Aijun Hao*. Saturated fatty acids activate microglia via Toll-like receptor 4/nuclear factor κB signaling. British journal of nutrition, 2012,107(2): 229-241

（7）Dexiang Liu^#, Zhen Wang^#, Shangming Liu, Fuwu Wang, Shidou Zhao, Aijun Hao*.Anti-inflammatory effects of fluoxetine in lipopolysaccharide (LPS)-stimulated microglial cells.Neuropharmacology, 2011,61(4): 592-599.

（8）Zhongwen Xie^#,Dexiang Liu^#, Shu Liu, Lindsay Calderon, Guogang Zhao, John Turk, Zhenheng Guo*. Identification of a cAMP-response element in the RGS2 promoter as a Key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultrured VSMC. J Biol Chem, 2011,286(52):44646-44658.

（9）Xueer Wang#, Yunkai Xie, Tiantian Zhang, Shishi bo, Xuemei Bai, Hansen Liu, Tong Li, Song liu, Yaru Zhou, Xiang Cong, Zhen Wang,Dexiang Liu*.Resveratrol reverses chronic restraint stress-induced depression-like behaviour: Involvement of BDNF level, ERK phosphorylation and expression of Bcl-2 and Bax in rats. Brain research bulletin, 2016, 125: 134-143

（10）Song liu^#, Tong Li, Hansen Liu, Xueer Wang, Shishi bo, Yunkai Xie,Xuemei Bai, Lin Wu, Zhen Wang,Dexiang Liu*.Resveratrol exerts antidepressant properties in the chronic unpredictable mild stress model through the regulation of oxidative stress and mTOR pathway in the rat hippocampus and prefrontal cortex. Behavioural brain research, 2016, 302: 191-199

（11）Qun Zhang^#, Lin Yuan^#, Qingrui Zhang, Yan Gao, Guangheng Liu, Meng Xiu, XiangWei, Zhen Wang* ,Dexiang Liu*. Resveratrol attenuates hypoxia-induced neurotoxicity through inhibiting microglial activation. Int Immunopharmacol, 2015, 28:578-587

（12）Li Ge^#, Liwei Liu^#, Hansen Liu, Song Liu, Hao Xue, Xueer Wang, Lin Yuan, Zhen Wang,Dexiang Liu*. Resveratrol abrogates lipopolysaccharide-induced depressive-like behavior, neuroinflammatory response, and CREB/BDNF signaling in mice. Eur J Pharmacol, 2015, 768:49-57

（13）Zhen Wang^#, Qingrui Zhang, Lin Yuan, Shuanglian Wang, Liwei Liu, Xudong Yang, Gang Li*, andDexiang Liu*. The effects of curcumin on depressive-like behavior in mice after lipopolysaccharide administration. Behav Brain Res, 2014,274:282-290

（14）Ze Gao^#, Hanyu Yuan, Minghan Sun, Zhen Wang, Yiqin He,Dexiang Liu*.The association of serotonin transporter gene polymorphism and geriatric depression: a meta-analysis. Neuroscience letters,2014, 578:148-52.

（15）Zhen Wang^#, JingminZhan, XueerWang, JianhuaGu, KaiXie, Qingrui Zhang,Dexiang Liu*. Sodium hydrosulfide prevents hypoxia-induced behavioral impairment in neonatal mice. Brain Res,2013,1538:126-134.

（16）Zhen Wang^#, Jianhua Gu, XueerWang , Kai Xie, Qinsong Luan, NianqingWan , Qun Zhang, Hong Jiang,Dexiang Liu*.Antidepressant-like activity of resveratrol treatment in the forced swim test and tail suspension test in mice: the HPA axis, BDNF expression and phosphorylation of ERK.Pharmacol Biochem Behav, 2013, 112:104-110.

（17）Hong Jiang^#, Zhen Wang^#, Yihe Wang, Kai Xie, Qun Zhang, Qinsong Luan, Wenqiang Chen,Dexiang Liu*. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry, 2013,47(2):33-39.