Zhuanchang Wu，Postdoctoral, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences,ShandongUniversity, Jinan, Shandong,China;

Research direction

HBV-host interaction and hepatocellular cancer development mechanism

Research funding

1.山东省博士基金，ZR2016HB16，抑癌基因ZHX2抑制HBV转录和复制的作用及分子机制研究，2016/11-2018/11，8万元，结题，主持

2.山东省重点研发计划（公益类），2019GSF108238，ABCF1识别HBV cccDNA诱导IFN-Lambda应答抑制HBV复制的作用机制及应用研究，2019/1-2021/12，15万元，在研，主持

3.国家自然科学基金青年基金，81902051，ABCF1识别HBV_cccDNA诱导IFN-Lambda应答抑制HBV复制的作用及分子机制，2020/1-2022/12，20万元，在研，主持

Published articles:

1.Wu, Z,Zhang R, Li Y, Shao D, Chen H, Jiang S, Ma Z*, Wang X*: C-terminal 20 residues of ORF3 protein of duck circovirus genotype 2 regulates the nuclear localization and inhibits apoptotic activity of ORF3 protein. Veterinary microbiology, 2018, 214:21-27.

2.Wu, Z^#,Tan S^#, Xu L, Gao L, Zhu H, Ma C, X. Liang*: NgAgo-gDNA system efficiently suppresses hepatitis B virus replication through accelerating decay of pregenomic RNA. Antiviral research, 2017, 145:20-23.

3.Wu Z^#, Wang X^#, Wei J, Li B, Shao D, Li Y, Liu K, Shi Y, Zhou B, Qiu Y, Ma Z*: Antiviral activity of doxycycline against vesicular stomatitis virus in vitro. FEMS Microbiol Lett,2015, 362(22).

Patents:

1.一种乙型肝炎病毒基因组DNA的5-乙炔基-2’脱氧尿嘧啶核苷的标记和检测方法，专利号：ZL201710153469.2