Bin Zhang

Associate Professor

Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong 250012, People’s Republic of China

Research Interests:

Pathophysiological mechanism of Parkinson's disease and Stroke

Education experience

2007.02~2008.08: Visiting scholar, Department of Neurological Surgery, University of California at Davis.

2005.09~2008.12: Ph.D. School of Medicine, Shandong University

2001.09~2004.06: M.S. School of Medicine, Shandong University

1991.09~1996.07: B.S. Hunan Medical University

Publications:

1. Wencheng Jian, Xinbing Wei, Lin Chen, Ziying Wang, Yu Sun, Shaowei Zhu, Haiyan Lou, Shaoqi Yan, Xinbing Li, Junlin Zhou,Bin Zhang. Inhibition of HDAC6 increases acetylation of peroxiredoxin1/2 and ameliorates 6-OHDA induced dopaminergic injury.Neuroscience Letters. 2017, 658: 114-120. (Corresponding author)

2.He M,Zhang B, Wei X, Wang Z, Fan B, Du P, Zhang Y, Jian W, Chen L, Wang L, Fang H, Li X, Wang PA, Yi F^*. HDAC4/5-HMGB1 signaling mediated by NADPH Oxidase activity contributes to cerebral ischemia/reperfusion injury.J Cell Mol Med.2013; 17(4): 531-542. (Co-first author)

3.Zhang B, West EJ, Van KC, Gurkoff GG, Zhou J, Zhang XM, Kozikowski AP, Lyeth BG. HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats.Brain Research. 2008, 1226: 181~191.

4.Di Giorgio AM, Hou Y, Zhao X,Zhang B, Lyeth BG, Russell MJ. Dimethyl sulfoxide provides neuroprotection in a traumatic brain injury model.Restorative Neurology and Neuroscience. 2008, 26(6):501～507.

5.Zhang B, Wei XB, Liu HQ, Wang LX, Sun R, Zhang XM. Protective Effects of Hydroxyethylpuerarin on Brain Astrocytes Injury Induced by Hydrogen peroxide.Acta Pharmaceutica Sinica.2006; 41 (2): 171~174.

6．Zhang B, Ding H，Wei XB，Wang LX. Pharmacodynamic Studies on shuanghuangyupi Frost.Chinese Traditional Patent Medicine.2002; 24 (11):891-892.

7.Zhang B，Wang ZY，Zhang XM，Wu BJ. The second generation antisense drug—mixed-backbone oligonucleotides.World Pharmacy.2001; 22 (3).

8．Zhang B，Zhang XM，Wu BJ. Current Drug Treatment and Treatment Patterns with Antihypertensive Drugs.World Pharmacy.1997;18 (3): 149～152.

9.Zhang B, West EJ, Van KC, Gurkoff GG, Kozikowski AP, Lyeth BG. HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats (abstract/poster). National Neurotrauma Symposium. Orlando, USA. July 27-30, 2008.Journal of Neurotrauma. 2008, 25(7): P317.

10. Yan SQ, Wei XB, Jian WC, Qin Y, Jiang F, Lou HY,Zhang B. Histone deacetylase 6 mediated NALP3 inflammasome activation contributes to dopaminergic injury in experimental models of Parkinson diseas (abstract). National Neuropsychopharmacology Symposium. Wuhan, China. Oct 12-15, 2018.Chin J Pharmacol Toxicol. 2018, 32(9): P686. (Corresponding author)

HONORS AND AWARDS:

Excellent Award of the Second Young Teachers' Teaching Competition of Shandong Medical University, Chian, 1998

Contact:

Telephone: 0531-88380515

Office: Department of Pharmacology (6208), School of Basic Medical Sciences, Shandong University, No.44 Wenhua Xi Road, Jinan, Shandong 250012, People’s Republic of China.

Email: binzhang@sdu.edu.cn