Yunxue Zhao

PhD, Associate Professor, Department of Pharmacology, School of Basic Medical Sciences, Shandong University

RESEARCH INTERESTS

Cancer Immunology and Immunotherapy, Nanomedicine

ACADEMIC & PROFESSIONAL EXPERIENCE

2016.07~present: Associate Professor, Department of Pharmacology, School of Basic Medical Sciences, Shandong University

2011.12~2016.07: Associate Professor, Department of Pharmacology, School of Medicine, Shandong University

2008.07~2011.11: Assistant Professor, Department of Pharmacology, School of Medicine, Shandong University

2007.05~2008.05: Postdoctor, School of Biomolecular and Biomedical Science and the UCD Conway Institute, University College Dublin

EDUCATION

2003.09~2007.01: Ph.D. School of Medicine and Pharmacy, Ocean University of China

2000.09~2003.07: M.S. Institute of Materia Medica, Shandong Academy of Medical Sciences

1996.09~2000.07: B.S. Shandong University of Traditional Chinese Medicine

SELECTED PUBLICATIONS

1.Weiqiang Jing, Fei Qin, Xing Guo, Yanlin Sun, Can Yan, Chunhong Qiu, Masato Tanakad, Benkang Shi*,Yunxue Zhao*, G-CSF mediates lung injury in mice with adenine-induced acute kidney injury.Int Immunopharmacol.2018, 63:1-8. *Corresponding author

2.2. Weiqiang Jing, Li Zhang, Fei Qin, XiuXiu Li, Xing Guo, Yue Li, Chunhong Qiu*, Yunxue Zhao*. Targeting macrophages for cancer therapy disrupts bone homeostasis and impairs bone marrow erythropoiesis in mice bearing Lewis lung carcinoma tumors.Cell Immunol. 2018, 331:168-177. *Corresponding author

3.Xing Jin, Xuejie Tan, Xiumei Zhang, Mingyong Han,Yunxue, Zhao*.In vitro and in vivo anticancer effects of singly protonated dehydronorcantharidin silver coordination polymer in CT-26 murine colon carcinoma model.Bioorg Med Chem Lett,2015, 25(20):4477-4480. *Corresponding author

4.Min Liu, Xing Jin, Xigan He, Ling Pan, Xiumei Zhang*,Yunxue, Zhao*. Macrophages support splenic erythropoiesis in 4T1 tumor-bearing mice.PloS One2015, 10(3):e0121921. *Corresponding author

5.Senpeng Li, Shuo Zhang, Xing Jin, Xuejie Tan, Jianfang Lou, Xiumei Zhang,Yunxue Zhao*. Singly protonated dehydronorcantharidin silver coordination polymer induces apoptosis of lung cancer cells via reactive oxygen species-mediated mitochondrial pathway.Eur J Med Chem.2014, 86:1-11. *Corresponding author

6.Min Liu, Xiaohu Gu, Ke Zhang, Yi Ding, Xinbing Wei, Xiumei Zhang*,Yunxue Zhao*. Gold nanoparticles trigger apoptosis and necrosis in lung cancer cells with low intracellular glutathione.J Nanopart Res.2013,15 (8):1745(1-14). *Corresponding author

7.Yunxue Zhao, Xiaohu Gu, Haizhang Ma, Xigan He, Min Liu, Yi Ding.Association of Glutathione Level and Cytotoxicity of Gold Nanoparticles in Lung Cancer Cells.J Phys Chem C,2011, 115 (26), 12797–12802.

8.Yunxue Zhao, Min Liu, Vincent Chagnault, Juying Wang, Xiumei Zhang, Paul V. Murphy. Biological study of a somatostatin mimetic based on the 1-deoxynojrimycin scaffold.Bioorg Med Chem Lett,2011,21(2):824-828

9.Yunxue Zhao, Yang G, Ren D, Zhang X, Yin Q, Sun X. Luteolin suppresses growth and migration of human lung cancer cells.Mol Biol Rep,2011, 38(2):1115-1119.

10.Yunxue Zhao, Wenjia Liu, Ying Zhou, Xiumei Zhang and Paul V. Murphy, N-(8-(3-Ethynylphenoxy)octyl-1-deoxynojirimycin Suppresses Growth and Migration of Human Lung Cancer Cells.Bioorg Med Chem Lett,2010,20(24):7540-7543.

11.Yunxue Zhao, Ying Zhou, Kathy M. O’ Boyle, Paul V. Murphy. Biological study of the angiogenesis inhibitor N-(8-(3-ethynylphenoxy)octyl-1-deoxynojirimycin.Chem Biol Drug Des,2010,75(6):570-577.

12.Yunxue Zhao, Ying Zhou, Kathy M. O’ Boyle, Paul V. Murphy. Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis.Bioorg Med Chem,2008, 16(12):6333-6337.

13.Yunxue Zhao, Jing Li, Yanli Xing, Jingjian Wang，Congxiao Lu, Xianliang Xin, Meiyu Geng. N-acetylglucosaminyltransferase V mediates cell migration and invasion of mouse mammary tumor cells 4TO7 via RhoA and Rac1 signaling pathway.Mol Cell Biochem,2008,309(1-2):199-20

TEACHING COURSES

Pharmacology

Pharmacology Experiment

CONTACTS

Tel: +86-531-88383146

E-mail: zhaoyunxue@sdu.edu.cn

Office number: 6204