Zhao Ling, PhD, Associate Professor
Education:
2005.9-2009.12 Shandong university, PhD of neurobiology
1996.9-1999.7 Shandong university, Master of physiology (major in Biomedical engineering)
1991.9-1996.7 Shandong medical university, Bachelor of clinical medicine
Research experience:
2010.9-present Shandong university as an associate professor
2010.3-2011.3 Shandong university postdoctoral fellow
Research direction:
Teaching: "cell biology", "neurobiology", PBL and "medical neurobiology".
Research Interests: Intracellular transport of receptor in nerve cells;inducedpluripotentstemcell
Research fund project:
1. Mechanism Underlying Syntaxin 8 Modulates the Post-Synthetic Trafficking of (TrkA) into the neuronal surface. National Natural Science Foundation of China 2012-2014
2. Study on the distribution of Tyrosine Kinase Receptor A on the surface of neuron cells and its mechanism. Excellent Young Scientists Foundation of Shandong Province 2011-2014
3. The research of Tyrosine Kinase Receptor A intracellular trafficking into the neuronal surface. China Postdoctoral Science Foundation 2010-2012
Main representative papers:
1.Wang, Y., X. Zhang, W. Tang, Z. Lin, L. Xu, R. Dong, Y. Li, J. Li, Z. Zhang, X. Li, L. Zhao, J. J. Wei, C. Shao, B. Kong and Z. Liu. "miR-130a upregulates mTOR pathway by targeting TSC1 and is transactivated by NF-kappaB in high-grade serous ovarian carcinoma." Cell Death Differ (2017) 24(12): 2089-2100.
2.Chen B,Zhao L1,Li X1,Ji YS1,Li N1,Xu XF1,Chen ZY2. Syntaxin 8 modulates the post-synthetic trafficking of the TrkA receptor and inflammatory paintransmission.J Biol Chem.(2014) Jul 11; 289(28): 19556-69. doi: 10.1074/jbc.M114.567925. Epub 2014 May 28. 114:110-121.
3.Zhao L, Sheng AL, Huang SH, Yin YX, Chen B, Li XZ, Zhang Y, Chen ZY*. Mechanism underlying activity-dependent insertion of TrkB into the neuronal surface.J Cell Sci. (2009). 122(Pt 17):3123-3136.
4.Huang SH1, Zhao L1, Sun ZP, Li XZ, Geng Z, Zhang KD, Chao MV, Chen ZY*. Essential role of Hrs in endocytic recycling of full-length TrkB receptor but not its isoform TrkB.T1.J Biol Chem. (2009).284(22):15126-36.
5.Wang Y1, Geng Z1, Zhao L1, Huang SH, Sheng AL, Chen ZY*. GDNF isoform affects intracellular trafficking and secretion of GDNF in neuronal cells. Brain Res. (2008). 1226: 1-7.
6.Yin YX, Sun ZP, Huang SH, Zhao L, Geng Z, Chen ZY*. RanBPM contributes to TrkB signaling and regulates brain-derived neurotrophic factor-induced neuronal morphogenesis and survival. J Neurochem. (2010).
7.Yin YX1,Sun ZP,Huang SH,Zhao L,Geng Z,Chen ZY. RanBPM contributes to TrkB signaling and regulates brain-derived neurotrophic factor-induced neuronal morphogenesis and survival.J Neurochem.2010 Jul;114(1):110-21. doi: 10.1111/j.1471-4159.2010.06745.x. Epub 2010 Apr 9.
Contact
Add: No.44 Wenhua Xi Road, Shandong University School of Basic Medical Sciences, Ji'nan, Shandong 250012, P.R.China
Tel: (0)86-531-88382329
